Ultrastructural Classification of Pituitary Adenomas

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Ultrastructural classification of pituitary adenomas.

Forty-eight surgically removed pituitary adenomas have been investigated by electron microscopy. Distinct differences in fine structural appearances permitted their separation into 5 classes: 1) Growth hormone, (GH)-cell tumors; 2) Prolactin cell tumors; 3) Mixed adenomas composed of GH and prolactin cells; 4) Adrenocorticotrophic-Melanocyte stimulating hormone (ACTH-MSH) cell tumors; 5) Undiff...

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Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study

Pituitary adenomas (PA) constitute about 10% of intracranial neoplasm. Most of them have its origin in adenohypophysis (Cury et al., 2009; Rosai, 1989). They occur most often in adults between the ages of 30 and 60 years, and may have slightly higher incidence in females in early life (20-45 years) and in males in later life (35-60 years) (Davis et al., 2001; McDowell et al., 2011). The majorit...

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Progress in the Diagnosis and Classification of Pituitary Adenomas

Pituitary adenomas are common neoplasms. Their classification is based upon size, invasion of adjacent structures, sporadic or familial cases, biochemical activity, clinical manifestations, morphological characteristics, response to treatment and recurrence. Although they are considered benign tumors, some of them are difficult to treat due to their tendency to recur despite standardized treatm...

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ژورنال

عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

سال: 1976

ISSN: 0317-1671,2057-0155

DOI: 10.1017/s0317167100025944